Scientists Develop World’s First Vaccine To Block Fentanyl From Entering The Brain

New Vaccine Stops Fentanyl From Entering The Brain & Stop Users From Getting High Or Risk Of Death

Scientists believe they’ve developed a vaccine that will block fentanyl from entering the brain and stop users from getting high — a breakthrough being hailed as a “game changer” in the fight against the opioid overdose epidemic.

In testing on rats, the vaccine “produced significant amounts” of anti-fentanyl antibodies that clung to the deadly addictive synthetic opioid, according to a study printed in the journal Pharmaceutics.

That prevented the drug “from entering the brain, allowing it to be eliminated out of the body via the kidneys,” said lead author Colin Haile of the University of Houston’s Drug Discovery Institute.

 

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“Thus, the individual will not feel the euphoric effects and can ‘get back on the wagon’ to sobriety,” said Haile, predicting it “could have a significant impact on a very serious problem plaguing society for years.”

Fentanyl is up to 50 times stronger than heroin, and a dose of only 2 milligrams — the size of two grains of rice — can prove fatal. According to the Centers for Disease Control and Prevention, more than 71,000 Americans died of fentanyl overdoses last year — almost 195 a day — by far the biggest cause of the overall 107,622 fatal overdoses.

The vaccine’s preclinical results “demonstrate efficacy in neutralizing” fentanyl, making it “a potential therapeutic for [overuse] and overdose in humans,” the study stated.

Another of the Texas university’s professors involved in the study, Therese Kosten, called it a potential “game changer.”